LAPAROSCOPIC INTERVENTION IN HIRSCHSPRUNG DISEASE - MARTIN DUHAMEL METHOD

Surgical Intervention to Rescue Hirschsprung Disease in a Rat Model

BACKGROUND/AIMS Rats with a spontaneous null mutation in endothelin receptor type B or Ednrb (sl/sl; spotting lethal) lack enteric neurons in the distal bowel and usually die within the first week after birth. This early postnatal lethality limits their use for examining the potential of cell therapy to treat Hirschsprung disease, and for studies of the influence of EDNRB on the mature CNS and ...

The Laparoscopic Assisted Duhamel Pull through Procedure for Hirschsprung’s Disease: Our Technique and Short Term Results

The Hirschsprung’s disease (HD) is characterized by absence of ganglion cells in the Myentric and Meissners plexus’ with nerve bundle hyperplasia [1,2]. The surgery for HD is changed from multistage surgery to single stage. Further, till date the superiority of either Duhamel, Swenson or soave procedure is comparable. It is unclear if one of these techniques yields significantly better general ...

Outcome comparison among laparoscopic Duhamel, laparotomic Duhamel, and transanal endorectal pull-through: a single-center, 18-year experience.

PURPOSE Transanal endorectal pull-through has changed the treatment of Hirschsprung's disease (HD) in the past decade. The aim of the study was to compare outcomes, obtained in a single center, with laparotomic Duhamel (LTD), laparoscopic Duhamel (LSD), and laparoscopic-assisted transanal endorectal pull-through (LTEPT). MATERIALS AND METHODS We retrospectively reviewed the charts of all pati...

Title Hirschsprung ' s disease

Total colonic aganglionosis in Hirschsprung disease.

Total colonic aganglionosis (TCA) is a relatively uncommon form of Hirschsprung disease (HSCR), occurring in approximately 2%-13% of cases. It can probably be classified as TCA (defined as aganglionosis extending from the anus to at least the ileocecal valve, but not >50 cm proximal to the ileocecal valve) and total colonic and small bowel aganglionosis, which may involve a very long segment of...